{"id":15587,"date":"2023-04-18T17:25:29","date_gmt":"2023-04-18T22:25:29","guid":{"rendered":"https:\/\/last-drum.flywheelsites.com\/?p=15587"},"modified":"2023-06-20T21:04:21","modified_gmt":"2023-06-21T02:04:21","slug":"gestational-influences-2023","status":"publish","type":"post","link":"https:\/\/autism.org\/gestational-influences-2023\/","title":{"rendered":"Gestational Influences and Autism"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_6 1_6 fusion-one-sixth fusion-column-first\" style=\"--awb-bg-size:cover;width:16.666666666667%;width:calc(16.666666666667% - ( ( 4% + 4% ) * 0.16666666666667 ) );margin-right: 4%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_2_3 2_3 fusion-two-third\" style=\"--awb-padding-top:40px;--awb-bg-size:cover;width:66.666666666667%;width:calc(66.666666666667% - ( ( 4% + 4% ) * 0.66666666666667 ) );margin-right: 4%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-text fusion-text-1\" style=\"--awb-text-transform:none;\"><p><span style=\"font-weight: 400;\"><a href=\"#jump\">Dr. Judy Van de Water, Ph.D.,<\/a> explores the role of gestational factors in the development of autism. She explains how maternal immune activation, antibody patterns, and immune markers play significant roles in neurodevelopment and may contribute to the etiology and phenotypic variation of autism. The speaker presents various investigations and critical findings. She asserts the need for further research on the interaction of these gestational influences with other genetic and environmental factors. Van de Water provides thanks and acknowledgments before the Q&amp;A.<\/span><\/p>\n<p>Take the knowledge quiz for this presentation <a href=\"#jump\">HERE<\/a><\/p>\n<\/div><div class=\"fusion-video fusion-youtube fusion-aligncenter\" style=\"--awb-max-width:1500px;--awb-max-height:844px;--awb-width:100%;\"><div class=\"video-shortcode\"><div class=\"fluid-width-video-wrapper\" style=\"padding-top:56.27%;\" ><iframe title=\"YouTube video player 1\" src=\"https:\/\/www.youtube.com\/embed\/qEMWA3zaC3g?wmode=transparent&autoplay=0\" width=\"1500\" height=\"844\" allowfullscreen allow=\"autoplay; fullscreen\"><\/iframe><\/div><\/div><\/div><div class=\"fusion-text fusion-text-2\" style=\"--awb-text-transform:none;\"><h2><b>In this webinar: <\/b><\/h2>\n<p><b>1:02 &#8211; <\/b><span style=\"font-weight: 400;\">Potential etiologies of autism<br \/>\n<\/span><b>3:03 &#8211; <\/b>Maternal Immune Activation Model<br \/>\n<b>5:30 &#8211; <\/b><span style=\"font-weight: 400;\">Research sample characteristics<br \/>\n<\/span><b>7:40 &#8211; <\/b><i>Study: Maternal prenatal cytokines<br \/>\n<\/i><b>11:05 &#8211; <\/b><i><span style=\"font-weight: 400;\">Study: Newborn immune markers<br \/>\n<\/span><\/i><b>15:06 &#8211; <\/b><i>Study: Effect of sex on newborn immune system profil<\/i>e<br \/>\n<b>17:30 &#8211; <\/b>Maternal autoantibody related autism subtype (MARA)<br \/>\n<b>19:25 &#8211; <\/b><span style=\"font-weight: 400;\">Target proteins and brain development<br \/>\n<\/span><b>20:46 &#8211;<\/b> <i><span style=\"font-weight: 400;\">Study: MAR antibody test<br \/>\n<\/span><\/i><b>24:26 &#8211; <\/b><i><span style=\"font-weight: 400;\">Study: Early markers of autism &#8211; prenatal validation<br \/>\n<\/span><\/i><b>27:40 &#8211; <\/b><span style=\"font-weight: 400;\">MAR antibody patterns phenotypes<br \/>\n<\/span><b>29:30 &#8211; <\/b><span style=\"font-weight: 400;\">Summary of clinical findings<br \/>\n<\/span><b>31:03 &#8211; <\/b><i><span style=\"font-weight: 400;\">Study: Translational animal model<br \/>\n<\/span><\/i><b>34:15 &#8211; <\/b><span style=\"font-weight: 400;\">Rodent model findings<br \/>\n<\/span><b>38:40 &#8211; <\/b><span style=\"font-weight: 400;\">Conclusions<br \/>\n<\/span><b>41:55 &#8211; <\/b><span style=\"font-weight: 400;\">Q &amp; A<\/span><\/p>\n<h2><strong>Introduction<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">Van de Water lists potential etiologies for autism, including genetic predisposition, immune dysregulation, and infections during gestation. She explains that maternal infection, specifically inflammation resulting from infection, has been implicated as a risk factor for autism and schizophrenia <\/span><b>(1:02)<\/b><span style=\"font-weight: 400;\">. The speaker introduces the Maternal Immune Activation Model, which proposes that when an inflammatory event occurs during pregnancy, the mother\u2019s immune response may be more active, leading to the transfer of different factors to the fetal compartment (e.g., cytokines) Such immune dysregulation can increase the risk of altered fetal neurodevelopment <\/span><b>(3:03)<\/b><span style=\"font-weight: 400;\">. Van de Water notes that genetic susceptibility, gestational timing, intensity of immune response and other postnatal events all play a role in autism etiology <\/span><b>(5:00)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2><strong>Inflammatory response during pregnancy<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">The presenter describes recent investigations into risk factors for autism and developmental delays <\/span><b>(5:30)<\/b><span style=\"font-weight: 400;\">. She summarizes sample collection and research methods for a study that assessed maternal prenatal cytokines in mothers of autistic children with intellectual delays (ID), mothers of autistic children without ID, and mothers of children with ID but not autism <\/span><b>(7:40)<\/b><span style=\"font-weight: 400;\">. Researchers found that mothers of autistic children with ID had the highest levels of inflammatory cytokines and chemokines compared to all other groups. This suggests, Van de Water continues, a lack of selective immune regulation in these women and a potential link between immune activation and ID in autistic individuals <\/span><b>(10:08)<\/b><span style=\"font-weight: 400;\">. A second study found that newborns diagnosed with autism and delayed development (DD) had lower levels of specific cytokines and chemokines at birth compared to those with typical development or DD without autism <\/span><b>(11:05)<\/b><span style=\"font-weight: 400;\">. Van de Water discusses particular chemokines and cytokines that may impact autism etiology <\/span><b>(13:30)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The speaker details another study investigating the effect of offspring sex on immune profiles at birth <\/span><b>(15:06)<\/b><span style=\"font-weight: 400;\">.<\/span> <span style=\"font-weight: 400;\">Researchers found that neonatal immune signatures differ by sex regardless of the neurodevelopmental outcome. However, control males had higher levels of certain immune markers than females, and autistic females with DD had higher levels than males with autism <\/span><b>(17:20)<\/b><span style=\"font-weight: 400;\">. The speaker asserts that such sex-specific differences in immune markers may contribute to the variability in autism phenotypes, highlighting the need for individualized treatments <\/span><b>(16:15)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2><strong>Maternal autoantibody-related autism<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">Van de Water discusses the maternal autoantibody-related autism subtype (MAR) (around 20% of cases), where mothers have antibodies that are reactive against proteins in the developing brain <\/span><b>(17:30)<\/b><span style=\"font-weight: 400;\">. She explains that during fetal development, the mother&#8217;s antibodies cross the placenta to provide immune protection for the fetus. In the case of MAR, some antibodies can bind to pre-neuronal cells, which leads to different brain development. The speaker presents a MAR antibody test designed by her team <\/span><b>(20:46)<\/b><span style=\"font-weight: 400;\">. Initial findings revealed antibody patterns specific to autism in 20% of the sample and that mothers with these antibodies were 31 times more likely to have a child with autism <\/span><b>(22:30)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The presenter outlines a second study that validated the MAR antibody test with prenatal data <\/span><b>(24:26)<\/b><span style=\"font-weight: 400;\">. They also found that specific MAR antibody patterns were associated with phenotypic differences in autism. Van de Water therefore asserts that these patterns could not only serve as autism biomarkers but could also inform more specific and individualized interventions <\/span><b>(27:40)<\/b><span style=\"font-weight: 400;\">. She summarizes clinical findings from the previous studies and notes that as autism incidence increases, they see an increase in MAR as well <\/span><b>(29:30)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2><strong>Translational animal models\u00a0<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">The speaker details translational animal models and why they are essential in preclinical trials. She explains how they used animal models to determine whether MAR autoantibodies are related to etiology or are just biomarkers <\/span><b>(31:03)<\/b><span style=\"font-weight: 400;\">. Animal studies generally include measures of behavior, brain scans, and cell cultures <\/span><b>(32:15)<\/b><span style=\"font-weight: 400;\">. Van de Water outlines an antibody study that found both mice and rats showed altered social behavior, self-grooming, and increased repetitive behaviors and produced the same antibodies found in humans with autism <\/span><b>(34:15)<\/b><span style=\"font-weight: 400;\">. These data, she continues, also exhibit differences in brain volume, with males and females displaying distinct patterns of brain development <\/span><b>(37:30)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Van de Water summarizes the main conclusions from the animal models. She highlights that gestational immune dysregulation may contribute to altered neurodevelopment and that antibodies localize to developing animals&#8217; brains. The speaker emphasizes that we see enlarged brains in humans, mice, monkeys, and rats with gestational exposure to MAR autoantibodies and underscores the structural effects of MAR antibodies and the usefulness of animal models <\/span><b>(38:40)<\/b><span style=\"font-weight: 400;\">. She provides acknowledgments and thanks to collaborators before the Q &amp; A <\/span><b>(41:55)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_6 1_6 fusion-one-sixth fusion-column-last\" style=\"--awb-bg-size:cover;width:16.666666666667%;width:calc(16.666666666667% - ( ( 4% + 4% ) * 0.16666666666667 ) );\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><div id=\"jump\" class=\"fusion-container-anchor\"><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_3 1_3 fusion-one-third fusion-column-first\" style=\"--awb-bg-size:cover;width:33.333333333333%;width:calc(33.333333333333% - ( ( 4% ) * 0.33333333333333 ) );margin-right: 4%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-text fusion-text-3\" style=\"--awb-text-transform:none;\"><h3>The speaker:<\/h3>\n<p><img decoding=\"async\" class=\"lazyload alignleft size-full wp-image-2758\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27107%27%20height%3D%27145%27%20viewBox%3D%270%200%20107%20145%27%3E%3Crect%20width%3D%27107%27%20height%3D%27145%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2019\/01\/Judy-VandeWater-Ph.D..jpg\" alt=\"\" width=\"107\" height=\"145\" \/>Judy Van de Water, PhD, joined the faculty in the Department of Internal Medicine at the University of California, Davis in 1999. In 2000, she also joined the faculty of the newly formed UC Davis M.I.N.D. Institute when she began her research on the immunobiology of autism. Dr. Van de Water\u2019s laboratory pursues research programs pertaining to autoimmune and clinical immune-based disorders including the biological aspects of autism spectrum disorders. The application of Dr. Van de Water\u2019s immunopathology background has been instrumental in the dissection of the immune anomalies noted in some individuals with autism, and in the differentiation of various autism behavioral phenotypes at a biological level. Most notable of these is the investigation of the maternal immune system as it relates to autism spectrum disorders, with particular emphasis on the presence of highly specific maternal autoantibodies to fetal brain proteins. Dr. Van de Water\u2019s seminal work in this area has led to a highly specific biomarker of autism risk as well as three patents leading to the commercialization of this technology. Dr. Van de Water is currently the Director of the NIEHS funded Center for Children\u2019s Environmental Health at UC Davis, investigating potential environmental risk factors contributing to the incidence and severity of childhood autism.<\/p>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion_builder_column_2_3 2_3 fusion-two-third fusion-column-last\" style=\"--awb-bg-size:cover;width:66.666666666667%;width:calc(66.666666666667% - ( ( 4% ) * 0.66666666666667 ) );\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-text fusion-text-4\"><h4>Take the knowledge quiz<\/h4>\n<p>Can&#8217;t see the quiz below? 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fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;margin-top:30px;width:100%;\"><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-recent-posts fusion-recent-posts-1 avada-container layout-default layout-columns-3\"><section class=\"fusion-columns columns fusion-columns-3 columns-3\"><article class=\"post fusion-column column col col-lg-4 col-md-4 col-sm-4\"><div class=\"fusion-flexslider fusion-flexslider-loading flexslider flexslider-hover-type-none\"><ul class=\"slides\"><li><a href=\"https:\/\/autism.org\/emerging-research-on-autism-rates-and-covid\/\" aria-label=\"Emerging Research on Autism Rates and Covid\" class=\"hover-type-none\"><img decoding=\"async\" width=\"700\" height=\"441\" src=\"https:\/\/autism.org\/wp-content\/uploads\/2021\/06\/AdobeStock_416761381-700x441.jpeg\" class=\"attachment-recent-posts size-recent-posts lazyload\" alt=\"Doctor is doing ultrasound screening for a pregnant woman\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%272560%27%20height%3D%271350%27%20viewBox%3D%270%200%202560%201350%27%3E%3Crect%20width%3D%272560%27%20height%3D%271350%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2021\/06\/AdobeStock_416761381-700x441.jpeg\" data-srcset=\"https:\/\/autism.org\/wp-content\/uploads\/2021\/06\/AdobeStock_416761381-320x202.jpeg 320w, https:\/\/autism.org\/wp-content\/uploads\/2021\/06\/AdobeStock_416761381-700x441.jpeg 700w\" data-sizes=\"auto\" \/><\/a><\/li><\/ul><\/div><div class=\"recent-posts-content\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2025-11-25T15:01:19-05:00<\/span><h4 class=\"entry-title\"><a href=\"https:\/\/autism.org\/emerging-research-on-autism-rates-and-covid\/\">Emerging Research on Autism Rates and Covid<\/a><\/h4><p class=\"meta\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2025-11-25T15:01:19-05:00<\/span><span>April 22nd, 2026<\/span><span class=\"fusion-inline-sep\">|<\/span><a href=\"https:\/\/autism.org\/category\/covid-19\/\" rel=\"category tag\">COVID-19<\/a>, <a href=\"https:\/\/autism.org\/category\/health\/\" rel=\"category tag\">Health<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/immune-issues\/\" rel=\"category tag\">Immune Issues<\/a>, <a href=\"https:\/\/autism.org\/category\/medical-care\/\" rel=\"category tag\">Medical Care<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/neurological\/\" rel=\"category tag\">Neurological<\/a>, <a href=\"https:\/\/autism.org\/category\/parenting\/\" rel=\"category tag\">Parenting<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/prenatal-health\/\" rel=\"category tag\">Pregnancy<\/a>, <a href=\"https:\/\/autism.org\/category\/research\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/research-webinar\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/webinars\/\" rel=\"category tag\">Webinar<\/a><span class=\"fusion-inline-sep\">|<\/span><\/p><p>  Free webinar at 1:00 p.m. Eastern time (US), April 22, 2026 Tune in to hear about the Columbia University COVID-19 Mother Baby Outcomes Initiative (COMBO), which resulted in the first report demonstrating that<\/p><\/div><\/article><article class=\"post fusion-column column col col-lg-4 col-md-4 col-sm-4\"><div class=\"fusion-flexslider fusion-flexslider-loading flexslider flexslider-hover-type-none\"><ul class=\"slides\"><li><a href=\"https:\/\/autism.org\/how-genetics-is-shaping-the-field-of-autism-research\/\" aria-label=\"How Genetics is Shaping the Field of Autism Research\" class=\"hover-type-none\"><img decoding=\"async\" width=\"700\" height=\"441\" src=\"https:\/\/autism.org\/wp-content\/uploads\/2018\/12\/genes-4-700x441.jpg\" class=\"attachment-recent-posts size-recent-posts lazyload\" alt=\"Medical professional conducting a test or analysis\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271000%27%20height%3D%27667%27%20viewBox%3D%270%200%201000%20667%27%3E%3Crect%20width%3D%271000%27%20height%3D%27667%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2018\/12\/genes-4-700x441.jpg\" data-srcset=\"https:\/\/autism.org\/wp-content\/uploads\/2018\/12\/genes-4-320x202.jpg 320w, https:\/\/autism.org\/wp-content\/uploads\/2018\/12\/genes-4-700x441.jpg 700w\" data-sizes=\"auto\" \/><\/a><\/li><\/ul><\/div><div class=\"recent-posts-content\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2026-02-23T14:19:25-05:00<\/span><h4 class=\"entry-title\"><a href=\"https:\/\/autism.org\/how-genetics-is-shaping-the-field-of-autism-research\/\">How Genetics is Shaping the Field of Autism Research<\/a><\/h4><p class=\"meta\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2026-02-23T14:19:25-05:00<\/span><span>January 27th, 2026<\/span><span class=\"fusion-inline-sep\">|<\/span><a href=\"https:\/\/autism.org\/category\/webinar\/environmental-factors\/\" rel=\"category tag\">Environmental Factors<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/genetics\/\" rel=\"category tag\">Genetics<\/a>, <a href=\"https:\/\/autism.org\/category\/health\/\" rel=\"category tag\">Health<\/a>, <a href=\"https:\/\/autism.org\/category\/medical-care\/\" rel=\"category tag\">Medical Care<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/neurological\/\" rel=\"category tag\">Neurological<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/research-webinar\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/category\/research\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/webinars\/\" rel=\"category tag\">Webinar<\/a><span class=\"fusion-inline-sep\">|<\/span><\/p><p>      Learn about how research on genetic influences is shaping our understanding of autism.      About the speaker: M. Pilar Trelles, MD, is a licensed and<\/p><\/div><\/article><article class=\"post fusion-column column col col-lg-4 col-md-4 col-sm-4\"><div class=\"fusion-flexslider fusion-flexslider-loading flexslider flexslider-hover-type-none\"><ul class=\"slides\"><li><a href=\"https:\/\/autism.org\/new-research-points-to-alterations-in-bpa-excretion-pathway-in-children-with-autism-adhd\/\" aria-label=\"New research points to alterations in BPA excretion pathway in children with autism, ADHD\" class=\"hover-type-none\"><img decoding=\"async\" width=\"700\" height=\"441\" src=\"https:\/\/autism.org\/wp-content\/uploads\/2024\/01\/water-bottles-sm-1200x556-1-700x441.jpg\" class=\"attachment-recent-posts size-recent-posts lazyload\" alt=\"Multiple water bottles with diverse colors and designs\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271200%27%20height%3D%27556%27%20viewBox%3D%270%200%201200%20556%27%3E%3Crect%20width%3D%271200%27%20height%3D%27556%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2024\/01\/water-bottles-sm-1200x556-1-700x441.jpg\" data-srcset=\"https:\/\/autism.org\/wp-content\/uploads\/2024\/01\/water-bottles-sm-1200x556-1-320x202.jpg 320w, https:\/\/autism.org\/wp-content\/uploads\/2024\/01\/water-bottles-sm-1200x556-1-700x441.jpg 700w\" data-sizes=\"auto\" \/><\/a><\/li><\/ul><\/div><div class=\"recent-posts-content\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/nicoleautism-com\/\" title=\"Posts by Nicole\" rel=\"author\">Nicole<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2024-09-05T15:08:54-05:00<\/span><h4 class=\"entry-title\"><a href=\"https:\/\/autism.org\/new-research-points-to-alterations-in-bpa-excretion-pathway-in-children-with-autism-adhd\/\">New research points to alterations in BPA excretion pathway in children with autism, ADHD<\/a><\/h4><p class=\"meta\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/nicoleautism-com\/\" title=\"Posts by Nicole\" rel=\"author\">Nicole<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2024-09-05T15:08:54-05:00<\/span><span>January 17th, 2024<\/span><span class=\"fusion-inline-sep\">|<\/span><a href=\"https:\/\/autism.org\/category\/news\/\" rel=\"category tag\">News<\/a><span class=\"fusion-inline-sep\">|<\/span><\/p><p>    Children with autism spectrum disorders (ASD) may have a reduced ability to detoxify the chemical bisphenol A (BPA), according to new research. BPA is an industrial \u201cplasticizer\u201d used in plastic water<\/p><\/div><\/article><article class=\"post fusion-column column col col-lg-4 col-md-4 col-sm-4\"><div class=\"fusion-flexslider fusion-flexslider-loading flexslider flexslider-hover-type-none\"><ul class=\"slides\"><li><a href=\"https:\/\/autism.org\/animal-study-adds-to-evidence-of-link-between-pyrethroids-and-autism\/\" aria-label=\"Animal study adds to evidence of link between pyrethroids and autism\" class=\"hover-type-none\"><img decoding=\"async\" width=\"700\" height=\"441\" src=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/10\/pesticide-700x441.jpeg\" class=\"attachment-recent-posts size-recent-posts lazyload\" alt=\"Worker spraying pesticides on tomato plants in a field\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%272560%27%20height%3D%271707%27%20viewBox%3D%270%200%202560%201707%27%3E%3Crect%20width%3D%272560%27%20height%3D%271707%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/10\/pesticide-700x441.jpeg\" data-srcset=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/10\/pesticide-320x202.jpeg 320w, https:\/\/autism.org\/wp-content\/uploads\/2023\/10\/pesticide-700x441.jpeg 700w\" data-sizes=\"auto\" \/><\/a><\/li><\/ul><\/div><div class=\"recent-posts-content\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2024-04-28T15:44:05-05:00<\/span><h4 class=\"entry-title\"><a href=\"https:\/\/autism.org\/animal-study-adds-to-evidence-of-link-between-pyrethroids-and-autism\/\">Animal study adds to evidence of link between pyrethroids and autism<\/a><\/h4><p class=\"meta\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2024-04-28T15:44:05-05:00<\/span><span>October 17th, 2023<\/span><span class=\"fusion-inline-sep\">|<\/span><a href=\"https:\/\/autism.org\/category\/news\/\" rel=\"category tag\">News<\/a><span class=\"fusion-inline-sep\">|<\/span><\/p><p>   A new animal study adds to evidence that prenatal exposure to common insecticides called pyrethroids may increase the likelihood of a child developing autism or another neurodevelopmental disorder. Melissa Curtis and colleagues,<\/p><\/div><\/article><article class=\"post fusion-column column col col-lg-4 col-md-4 col-sm-4\"><div class=\"fusion-flexslider fusion-flexslider-loading flexslider flexslider-hover-type-none\"><ul class=\"slides\"><li><a href=\"https:\/\/autism.org\/prenatal-exposure-to-cannabis-may-increase-likelihood-of-autism\/\" aria-label=\"Prenatal exposure to cannabis may increase likelihood of autism\" class=\"hover-type-none\"><img decoding=\"async\" width=\"700\" height=\"441\" src=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/08\/Medical-marijuana-700x441.jpeg\" class=\"attachment-recent-posts size-recent-posts lazyload\" alt=\"Marijuana and cannabis oil bottles\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%272560%27%20height%3D%271702%27%20viewBox%3D%270%200%202560%201702%27%3E%3Crect%20width%3D%272560%27%20height%3D%271702%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/08\/Medical-marijuana-700x441.jpeg\" data-srcset=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/08\/Medical-marijuana-320x202.jpeg 320w, https:\/\/autism.org\/wp-content\/uploads\/2023\/08\/Medical-marijuana-700x441.jpeg 700w\" data-sizes=\"auto\" \/><\/a><\/li><\/ul><\/div><div class=\"recent-posts-content\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2024-04-28T15:45:52-05:00<\/span><h4 class=\"entry-title\"><a href=\"https:\/\/autism.org\/prenatal-exposure-to-cannabis-may-increase-likelihood-of-autism\/\">Prenatal exposure to cannabis may increase likelihood of autism<\/a><\/h4><p class=\"meta\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2024-04-28T15:45:52-05:00<\/span><span>August 29th, 2023<\/span><span class=\"fusion-inline-sep\">|<\/span><a href=\"https:\/\/autism.org\/category\/news\/\" rel=\"category tag\">News<\/a><span class=\"fusion-inline-sep\">|<\/span><\/p><p>   Cannabis use during pregnancy may alter placental and fetal DNA methylation (the process of turning genes \u201con\u201d and \u201coff\u201d) in ways that increase the likelihood of autism spectrum disorder (ASD) or other<\/p><\/div><\/article><article class=\"post fusion-column column col col-lg-4 col-md-4 col-sm-4\"><div class=\"fusion-flexslider fusion-flexslider-loading flexslider flexslider-hover-type-none\"><ul class=\"slides\"><li><a href=\"https:\/\/autism.org\/gestational-influences-2023\/\" aria-label=\"Gestational Influences and Autism\" class=\"hover-type-none\"><img decoding=\"async\" width=\"700\" height=\"441\" src=\"https:\/\/autism.org\/wp-content\/uploads\/2016\/09\/Untitled-design-67-700x441.jpg\" class=\"attachment-recent-posts size-recent-posts lazyload\" alt=\"pregnant woman, autism leucovorin and acetaminophen\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271280%27%20height%3D%27720%27%20viewBox%3D%270%200%201280%20720%27%3E%3Crect%20width%3D%271280%27%20height%3D%27720%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2016\/09\/Untitled-design-67-700x441.jpg\" data-srcset=\"https:\/\/autism.org\/wp-content\/uploads\/2016\/09\/Untitled-design-67-320x202.jpg 320w, https:\/\/autism.org\/wp-content\/uploads\/2016\/09\/Untitled-design-67-700x441.jpg 700w\" data-sizes=\"auto\" \/><\/a><\/li><\/ul><\/div><div class=\"recent-posts-content\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/autismadmin\/\" title=\"Posts by autismAdmin\" rel=\"author\">autismAdmin<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2023-06-20T21:04:21-05:00<\/span><h4 class=\"entry-title\"><a href=\"https:\/\/autism.org\/gestational-influences-2023\/\">Gestational Influences and Autism<\/a><\/h4><p class=\"meta\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/autismadmin\/\" title=\"Posts by autismAdmin\" rel=\"author\">autismAdmin<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2023-06-20T21:04:21-05:00<\/span><span>April 18th, 2023<\/span><span class=\"fusion-inline-sep\">|<\/span><a href=\"https:\/\/autism.org\/category\/anxiety-2\/\" rel=\"category tag\">Anxiety<\/a>, <a href=\"https:\/\/autism.org\/category\/autism-spectrum-disorders\/\" rel=\"category tag\">Autism Spectrum Disorders<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/immune-issues\/\" rel=\"category tag\">Immune Issues<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/prenatal-health\/\" rel=\"category tag\">Pregnancy<\/a>, <a href=\"https:\/\/autism.org\/category\/autism-spectrum-disorders\/ways-to-help\/\" rel=\"category tag\">Ways to Help<\/a>, <a href=\"https:\/\/autism.org\/webinars\/\" rel=\"category tag\">Webinar<\/a><span class=\"fusion-inline-sep\">|<\/span><\/p><p>  Dr. Judy Van de Water, Ph.D., explores the role of gestational factors in the development of autism. She explains how maternal immune activation, antibody patterns, and immune markers play significant roles in neurodevelopment<\/p><\/div><\/article><\/section><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":8130,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9449,21,31,33,9475,24],"tags":[3537,9695,9697,9696,3525,4128,72],"class_list":["post-15587","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-anxiety-2","category-autism-spectrum-disorders","category-immune-issues","category-prenatal-health","category-ways-to-help","category-webinar","tag-development","tag-gestational-influences","tag-immunological","tag-neurodevelopmental","tag-pregnancy","tag-prenatal","tag-research","webinar-author-judy-van-de-water-phd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.6 (Yoast SEO v27.1.1) - 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