{"id":16995,"date":"2024-03-05T09:39:01","date_gmt":"2024-03-05T14:39:01","guid":{"rendered":"https:\/\/last-drum.flywheelsites.com\/?p=16995"},"modified":"2024-07-17T09:16:42","modified_gmt":"2024-07-17T14:16:42","slug":"gut-autism","status":"publish","type":"post","link":"https:\/\/autism.org\/gut-autism\/","title":{"rendered":"The Gut, Autism, and Mental Health"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_6 1_6 fusion-one-sixth fusion-column-first\" style=\"--awb-padding-top:80px;--awb-bg-size:cover;width:13.3333%; margin-right: 4%;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\"><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;margin-top:40px;width:100%;\"><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_2_3 2_3 fusion-two-third\" style=\"--awb-padding-top:80px;--awb-bg-size:cover;width:65.3333%; margin-right: 4%;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\"><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;width:100%;\"><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-text fusion-text-1\" style=\"--awb-text-transform:none;\"><p><span style=\"font-weight: 400;\"><a href=\"#Jump\">Dr. Calliope Holingue, MPH, Ph.D.<\/a>, provides an overview of the intersection between the gut, autism, and well-being. She outlines recent studies on the GI needs and experiences of autistic individuals and discusses the complex pathways of connection between the gut and autism. The presenter summarizes GI-autism research to date, highlighting the need for screening tools specific to autistic GI experiences. Diet change and Fecal Matter Transplant are outlined as microbial interventions in autism. Holingue provides tips for recognizing GI distress and discusses future directions for research and interventions before the Q&amp;A.\u00a0<\/span><\/p>\n<\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;width:100%;\"><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-video fusion-youtube fusion-aligncenter\" style=\"--awb-max-width:600px;--awb-max-height:360px;--awb-width:100%;\"><div class=\"video-shortcode\"><div class=\"fluid-width-video-wrapper\" style=\"padding-top:60%;\" ><iframe title=\"YouTube video player 1\" src=\"https:\/\/www.youtube.com\/embed\/2jWPe8nEuGs?wmode=transparent&autoplay=0\" width=\"600\" height=\"360\" allowfullscreen allow=\"autoplay; fullscreen\"><\/iframe><\/div><\/div><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;margin-top:30px;width:100%;\"><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-text fusion-text-2\" style=\"--awb-text-transform:none;\"><h2><strong>In this webinar:<\/strong><\/h2>\n<p><strong>1:00<\/strong> &#8211; Outline<br \/>\n<strong>1:50<\/strong> &#8211; Autism and gastrointestinal issues<br \/>\n<strong>4:15<\/strong> &#8211; Common GI symptoms<br \/>\n<strong>6:20<\/strong> &#8211; Study: Qualitative study of families with autistic children with GI issues<br \/>\n<strong>12:00<\/strong> &#8211; Study: GI experiences and needs of autistic adults<br \/>\n<strong>16:20<\/strong> &#8211; Linking GI symptoms and autism<br \/>\n<strong>21:04<\/strong> &#8211; Intersection of autism and GI research<br \/>\n<strong>25:55<\/strong> &#8211; Microbiome interventions in autism<br \/>\n<strong>32:10<\/strong> &#8211; Fecal matter transplant (FMT)<br \/>\n<strong>34:00<\/strong> &#8211; Study: Autism and microbiota transfer therapy<br \/>\n<strong>39:55<\/strong> &#8211; Recognizing GI distress in autism<br \/>\n<strong>43:05<\/strong> &#8211; Quotes from parents<br \/>\n<strong>44:24<\/strong> &#8211; Gastrointestinal and related behaviors inventory (GIRBI)<br \/>\n<strong>45:50<\/strong> &#8211; Future directions<br \/>\n<strong>47:45<\/strong> &#8211; Q&amp;A<\/p>\n<h2><strong>Autism and gastrointestinal issues<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">Holingue outlines common clinical characteristics of autism and explains how co-occurring medical conditions affect autism heterogeneity <\/span><b>(1:50)<\/b><span style=\"font-weight: 400;\">. People with autism often have complex healthcare needs but consistently experience a lower quality of care and assistance across their lifetime <\/span><b>(3:05)<\/b><span style=\"font-weight: 400;\">. The speaker explains that gastrointestinal (GI) issues like constipation, diarrhea, and abdominal pain are incredibly common in autism, occurring in 47% of autistic participants in a recent meta-analysis <\/span><b>(4:15)<\/b><span style=\"font-weight: 400;\">. She notes that GI distress has been linked to co-occurring conditions like seizures, sleep disorders, and functional behavior difficulties <\/span><b>(5:30)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3><strong>Study: Qualitative assessment of GI issues in autistic children and their families<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">The speaker outlines her 2022 publication in <\/span><i><span style=\"font-weight: 400;\">Autism,<\/span><\/i><span style=\"font-weight: 400;\"> assessing the experiences of autistic children with GI issues and their families. Researchers derived four main themes from 12 parent interviews <\/span><b>(6:20)<\/b><span style=\"font-weight: 400;\">. First, autistic children often have difficulty verbally communicating the presence of GI symptoms, and second, GI issues impact a child\u2019s overall well-being and ability to fully engage in activities like school or social gatherings <\/span><b>(7:40)<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The third theme to emerge was how GI issues impact the family\u2019s well-being due to parental frustrations, financial stressors, and limitations on family activities <\/span><b>(9:00)<\/b><span style=\"font-weight: 400;\">. Finally, theme four highlights the challenges parents experience with finding accessible quality care for their children. Many noted lengthy, complicated processes, medical offices not conducive to autism, and a lack of education and experience in healthcare providers <\/span><b>(10:12)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3><strong>Study: GI experiences and needs for adults with autism<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">Holingue outlines a study exploring the GI experiences of autistic adults (in preparation for publication). The study aims to investigate the needs and priorities of autistic adults and develop recommendations for research and support <\/span><b>(12:00)<\/b><span style=\"font-weight: 400;\">. Similar to the first study, participants said that GI symptoms profoundly impact their ability to create relationships, work, and live comfortably (overall well-being). They also described common triggers for GI issues, including stress, sensory overwhelm, and changes in routine, and highlighted frustrating and unhelpful experiences with the healthcare systems <\/span><b>(13:15)<\/b><span style=\"font-weight: 400;\">. To improve GI health in autistic adults, the researchers recommend more training around interoception, anxiety, and advocacy for adults with autism. Similarly, they assert the need for increased healthcare provider training on assessing and treating complex health issues and autism accommodations <\/span><b>(15:15)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2><strong>The intersection of autism and GI issues<\/strong><\/h2>\n<h3><strong>Pathways of connection<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">Holingue claims that pathways linking autism and GI issues are complex. For example, common co-occurring conditions, like anxiety, sleep problems, and restrictive diets, drastically alter the gut microbiome <\/span><b>(16:20)<\/b><span style=\"font-weight: 400;\">. Similarly, GI symptoms can exacerbate irritability, anxiety, and other behaviors related to pain or discomfort<\/span><b> (19:00)<\/b><span style=\"font-weight: 400;\">. The presenter touches on biological pathways that interact with GI health including the microbiome, vagus nerve, immune system modulation, gut permeability, and serotonin production <\/span><b>(20:14)<\/b><span style=\"font-weight: 400;\">. She explains that maternal microbiomes interact with fetal immune systems and how early life exposures shape the development of the microbiome (i.e., delivery mode, diet\/breastfeeding) <\/span><b>(29:00)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3><strong>History of GI-autism research<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">The speaker outlines autism-GI research starting from the early 2000s. She briefly summarizes initial observations <\/span><b>(21:04)<\/b><span style=\"font-weight: 400;\">, the discovery of the gut-brain axis <\/span><b>(22:15)<\/b><span style=\"font-weight: 400;\">, how microbiome diversity can inform behavior and treatment <\/span><b>(22:40)<\/b><span style=\"font-weight: 400;\">, and the beginning of intervention studies <\/span><b>(23:35)<\/b><span style=\"font-weight: 400;\">. Contemporary research, Holingue continues, focuses on understanding the mechanisms by which the gut microbiome influences the brain and how the environment influences the composition of the gut microbiome <\/span><b>(24:30)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2><strong>Microbiome interventions in autism<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">Microbial interventions hold promise in autism because they are modifiable for individuals across heterogeneities. The speaker notes that most studies to date are strictly pediatric <\/span><b>(25:55)<\/b><span style=\"font-weight: 400;\">. Findings across the field are divergent and inconclusive due to small cohorts, different comparison groups, and autism heterogeneity <\/span><b>(26:30)<\/b><span style=\"font-weight: 400;\">. The presenter asserts that failure to control for potential confounders, or other things that could impact the microbiome (i.e., diet, antibiotics, medications, etc.) is a major limiting factor across studies.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Diet change is a common intervention that affects gut microbial composition <\/span><b>(30:50)<\/b><span style=\"font-weight: 400;\">. Holingue describes fecal matter transplant (FMT), where a healthy donor provides feces (after extensive screening and safety measures), which contains microbiota needed by someone with a specific health condition. The cleaned microbiota is delivered to the recipient via pill, drink, or endoscopy <\/span><b>(32:10)<\/b><span style=\"font-weight: 400;\">. She discusses the difference between intestinal mucosa (fecal matter) and the microbiome, noting the safety and ethical nuances associated with FMT <\/span><b>(28:00)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3><strong>Study: Autism and microbiota transfer therapy<\/strong><\/h3>\n<p><span style=\"font-weight: 400;\">Holingue outlines an FMT study by Kange et al. (2019) in which parents collected stool samples and recorded symptoms during treatment <\/span><b>(35:12)<\/b><span style=\"font-weight: 400;\">. Microbiome results showed that autism gut bacteria were less diverse at baseline but increased throughout the treatment, ending with a similar composition to controls. Some long-term effects were recorded <\/span><b>(35:20)<\/b><span style=\"font-weight: 400;\">. There was a significant correlation between changes in GI composition and autism behaviors, meaning that as GI symptoms improved, associated behaviors decreased. The treatment was generally well tolerated, with few temporary adverse effects <\/span><b>(36:16)<\/b><span style=\"font-weight: 400;\">. The speaker discusses study limitations, including a lack of a placebo group and randomization <\/span><b>(37:20)<\/b><span style=\"font-weight: 400;\">. She considers the difficulty and importance of disentangling treatment effects from other drivers and notes the small sample size in this study <\/span><b>(38:10)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2><strong>Recognizing and treating GI issues in autism<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">The presenter briefly discusses symptoms and signs of GI distress in autism <\/span><b>(39:55)<\/b><span style=\"font-weight: 400;\">. She underscores that children, in general, have difficulty communicating pain and that this is often exacerbated in children with neurodevelopmental conditions <\/span><b>(41:00)<\/b><span style=\"font-weight: 400;\">. Holingue discusses a recent analysis that found that symptom estimates vary according to how they are measured (i.e., parents\/practitioners\/complex data) and that existing measurements were not developed for the autistic population <\/span><b>(41:44)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Parents are often relied on to detect GI problems in their children. The presenter lists some tell-tale signs<\/span> <span style=\"font-weight: 400;\">of GI distress in autistic children and asserts the need for assessment tools specific to GI experiences in autism <\/span><b>(42:35)<\/b><span style=\"font-weight: 400;\">. She outlines the Gastrointestinal and Related Behaviors Inventory (GIRBI), which assesses symptoms, bowel movements, and other behaviors potentially related to GI issues <\/span><b>(44:24)<\/b><span style=\"font-weight: 400;\">.\u00a0 Results from the pilot GIRBI questionnaire show high convergent validity, high sensitivity in predicting parent-report diagnosis, and a 7-factor solution to recognizing GI issues in autism <\/span><b>(45:40)<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2><strong>Future directions<\/strong><\/h2>\n<p><span style=\"font-weight: 400;\">The speaker asserts that future work on GI measurements should include multiple versions of the GIRBI, with specific attention given to adults and older adults with autism. Future assessments should also incorporate biospecimens with report measures and include self-reports, caregiver reports, and more clinical evaluations <\/span><b>(45:50)<\/b><span style=\"font-weight: 400;\">. Holingue provides thanks and acknowledgments <\/span><b>(47:12)<\/b><span style=\"font-weight: 400;\"> before the Q&amp;A, where she discusses food allergies, gluten vs. celiac, recommended diets, advocacy in medical settings, and how modes of delivery impact an infant\u2019s gut <\/span><b>(47:45)<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;margin-top:40px;width:100%;\"><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_6 1_6 fusion-one-sixth fusion-column-last\" style=\"--awb-padding-top:80px;--awb-bg-size:cover;width:13.3333%;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\"><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;margin-top:40px;width:100%;\"><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><div id=\"Jump\" class=\"fusion-container-anchor\"><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 has-pattern-background has-mask-background nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_3 1_3 fusion-one-third fusion-column-first\" style=\"--awb-bg-size:cover;width:33.333333333333%;width:calc(33.333333333333% - ( ( 4% ) * 0.33333333333333 ) );margin-right: 4%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-text fusion-text-3\" style=\"--awb-text-transform:none;\"><h3>The speaker:<\/h3>\n<p><img decoding=\"async\" class=\"lazyload  wp-image-16996 alignleft\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27121%27%20height%3D%27158%27%20viewBox%3D%270%200%20121%20158%27%3E%3Crect%20width%3D%27121%27%20height%3D%27158%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/09\/calliope.jpg\" alt=\"\" width=\"121\" height=\"158\" \/><strong>Calliope Holingue, MPH, PhD<\/strong> is a research faculty member at\u00a0the\u00a0Center for Autism and Related Disorders\u00a0at Kennedy Krieger Institute. A psychiatric epidemiologist by training, she also has a joint academic appointment as an assistant professor from the Department of Mental Health at\u00a0Johns Hopkins Bloomberg School of Public Health.<\/p>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion_builder_column_2_3 2_3 fusion-two-third fusion-column-last\" style=\"--awb-bg-size:cover;width:66.666666666667%;width:calc(66.666666666667% - ( ( 4% ) * 0.66666666666667 ) );\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-text fusion-text-4\"><h4>Take the knowledge quiz<\/h4>\n<p>Can&#8217;t see the quiz below? 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fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;margin-top:30px;width:100%;\"><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-recent-posts fusion-recent-posts-1 avada-container layout-default layout-columns-3\"><section class=\"fusion-columns columns fusion-columns-3 columns-3\"><article class=\"post fusion-column column col col-lg-4 col-md-4 col-sm-4\"><div class=\"fusion-flexslider fusion-flexslider-loading flexslider flexslider-hover-type-none\"><ul class=\"slides\"><li><a href=\"https:\/\/autism.org\/2026-research-updates-gi-symptoms-behavior\/\" aria-label=\"2026 Research Updates: GI Symptoms &#038; Behavior\" class=\"hover-type-none\"><img decoding=\"async\" width=\"700\" height=\"441\" src=\"https:\/\/autism.org\/wp-content\/uploads\/2020\/09\/AdobeStock_154166314-700x441.jpeg\" class=\"attachment-recent-posts size-recent-posts lazyload\" alt=\"Gut-brain connection or gut brain axis. Concept art showing a connection from the gut to the brain. 3d illustration.\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%272560%27%20height%3D%271556%27%20viewBox%3D%270%200%202560%201556%27%3E%3Crect%20width%3D%272560%27%20height%3D%271556%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2020\/09\/AdobeStock_154166314-700x441.jpeg\" data-srcset=\"https:\/\/autism.org\/wp-content\/uploads\/2020\/09\/AdobeStock_154166314-320x202.jpeg 320w, https:\/\/autism.org\/wp-content\/uploads\/2020\/09\/AdobeStock_154166314-700x441.jpeg 700w\" data-sizes=\"auto\" \/><\/a><\/li><\/ul><\/div><div class=\"recent-posts-content\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2026-03-10T17:36:23-05:00<\/span><h4 class=\"entry-title\"><a href=\"https:\/\/autism.org\/2026-research-updates-gi-symptoms-behavior\/\">2026 Research Updates: GI Symptoms &#038; Behavior<\/a><\/h4><p class=\"meta\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2026-03-10T17:36:23-05:00<\/span><span>December 2nd, 2026<\/span><span class=\"fusion-inline-sep\">|<\/span><a href=\"https:\/\/autism.org\/category\/webinar\/anxiety\/\" rel=\"category tag\">Anxiety<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/challenging-behaviors\/\" rel=\"category tag\">Challenging Behaviors<\/a>, <a href=\"https:\/\/autism.org\/category\/depression\/\" rel=\"category tag\">depression<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/gastrointestinal-webinar\/\" rel=\"category tag\">Gastrointestinal<\/a>, <a href=\"https:\/\/autism.org\/category\/health\/\" rel=\"category tag\">Health<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/immune-issues\/\" rel=\"category tag\">Immune Issues<\/a>, <a href=\"https:\/\/autism.org\/category\/medical-care\/\" rel=\"category tag\">Medical Care<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/neurological\/\" rel=\"category tag\">Neurological<\/a>, <a href=\"https:\/\/autism.org\/category\/parenting\/\" rel=\"category tag\">Parenting<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/prenatal-health\/\" rel=\"category tag\">Pregnancy<\/a>, <a href=\"https:\/\/autism.org\/category\/research\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/research-webinar\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/category\/self-injury-2\/\" rel=\"category tag\">Self Injury<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/self-injury\/\" rel=\"category tag\">Self-Injury<\/a>, <a href=\"https:\/\/autism.org\/webinars\/\" rel=\"category tag\">Webinar<\/a><span class=\"fusion-inline-sep\">|<\/span><\/p><p>  Free webinar at 1:00 p.m. Eastern time (US), December 2, 2026 Dr. Bradley Ferguson, PhD,\u00a0a\u00a02024 research grant recipient, will share emerging research on the interaction of GI symptoms and behavior in autism. <\/p><\/div><\/article><article class=\"post fusion-column column col col-lg-4 col-md-4 col-sm-4\"><div class=\"fusion-flexslider fusion-flexslider-loading flexslider flexslider-hover-type-none\"><ul class=\"slides\"><li><a href=\"https:\/\/autism.org\/research-updates-gastrointestinal-issues-and-autism\/\" aria-label=\"Research Updates: Gastrointestinal Issues and Autism\" class=\"hover-type-none\"><img decoding=\"async\" width=\"500\" height=\"334\" src=\"https:\/\/autism.org\/wp-content\/uploads\/2019\/01\/gastro.jpg\" class=\"attachment-recent-posts size-recent-posts lazyload\" alt=\"man with gut problems\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27500%27%20height%3D%27334%27%20viewBox%3D%270%200%20500%20334%27%3E%3Crect%20width%3D%27500%27%20height%3D%27334%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2019\/01\/gastro.jpg\" data-srcset=\"https:\/\/autism.org\/wp-content\/uploads\/2019\/01\/gastro-200x134.jpg 200w, https:\/\/autism.org\/wp-content\/uploads\/2019\/01\/gastro-300x200.jpg 300w, https:\/\/autism.org\/wp-content\/uploads\/2019\/01\/gastro-400x267.jpg 400w, https:\/\/autism.org\/wp-content\/uploads\/2019\/01\/gastro.jpg 500w\" data-sizes=\"auto\" \/><\/a><\/li><\/ul><\/div><div class=\"recent-posts-content\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2026-02-18T13:02:59-05:00<\/span><h4 class=\"entry-title\"><a href=\"https:\/\/autism.org\/research-updates-gastrointestinal-issues-and-autism\/\">Research Updates: Gastrointestinal Issues and Autism<\/a><\/h4><p class=\"meta\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2026-02-18T13:02:59-05:00<\/span><span>July 29th, 2026<\/span><span class=\"fusion-inline-sep\">|<\/span><a href=\"https:\/\/autism.org\/category\/covid-19\/\" rel=\"category tag\">COVID-19<\/a>, <a href=\"https:\/\/autism.org\/category\/health\/\" rel=\"category tag\">Health<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/immune-issues\/\" rel=\"category tag\">Immune Issues<\/a>, <a href=\"https:\/\/autism.org\/category\/medical-care\/\" rel=\"category tag\">Medical Care<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/neurological\/\" rel=\"category tag\">Neurological<\/a>, <a href=\"https:\/\/autism.org\/category\/parenting\/\" rel=\"category tag\">Parenting<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/prenatal-health\/\" rel=\"category tag\">Pregnancy<\/a>, <a href=\"https:\/\/autism.org\/category\/research\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/research-webinar\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/webinars\/\" rel=\"category tag\">Webinar<\/a><span class=\"fusion-inline-sep\">|<\/span><\/p><p>  Free webinar at 1:00 p.m. Eastern time (US), July 29, 2026 Harland Winter, MD, will discuss his research on gastrointestinal conditions in individuals with autism. Dr. Winter is an active investigator and educator<\/p><\/div><\/article><article class=\"post fusion-column column col col-lg-4 col-md-4 col-sm-4\"><div class=\"fusion-flexslider fusion-flexslider-loading flexslider flexslider-hover-type-none\"><ul class=\"slides\"><li><a href=\"https:\/\/autism.org\/research-updates-microbiome-research-and-autism\/\" aria-label=\"Research Updates: Microbiome Research and Autism\" class=\"hover-type-none\"><img decoding=\"async\" width=\"700\" height=\"441\" src=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/08\/gut-microbiome-again-700x441.jpeg\" class=\"attachment-recent-posts size-recent-posts lazyload\" alt=\"Black and white drawing for human torso with multicolored bacteria and yeasts in digestive tract\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%272560%27%20height%3D%271706%27%20viewBox%3D%270%200%202560%201706%27%3E%3Crect%20width%3D%272560%27%20height%3D%271706%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/08\/gut-microbiome-again-700x441.jpeg\" data-srcset=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/08\/gut-microbiome-again-320x202.jpeg 320w, https:\/\/autism.org\/wp-content\/uploads\/2023\/08\/gut-microbiome-again-700x441.jpeg 700w\" data-sizes=\"auto\" \/><\/a><\/li><\/ul><\/div><div class=\"recent-posts-content\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2026-02-09T15:13:30-05:00<\/span><h4 class=\"entry-title\"><a href=\"https:\/\/autism.org\/research-updates-microbiome-research-and-autism\/\">Research Updates: Microbiome Research and Autism<\/a><\/h4><p class=\"meta\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2026-02-09T15:13:30-05:00<\/span><span>May 20th, 2026<\/span><span class=\"fusion-inline-sep\">|<\/span><a href=\"https:\/\/autism.org\/category\/covid-19\/\" rel=\"category tag\">COVID-19<\/a>, <a href=\"https:\/\/autism.org\/category\/health\/\" rel=\"category tag\">Health<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/immune-issues\/\" rel=\"category tag\">Immune Issues<\/a>, <a href=\"https:\/\/autism.org\/category\/medical-care\/\" rel=\"category tag\">Medical Care<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/neurological\/\" rel=\"category tag\">Neurological<\/a>, <a href=\"https:\/\/autism.org\/category\/parenting\/\" rel=\"category tag\">Parenting<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/prenatal-health\/\" rel=\"category tag\">Pregnancy<\/a>, <a href=\"https:\/\/autism.org\/category\/research\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/research-webinar\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/webinars\/\" rel=\"category tag\">Webinar<\/a><span class=\"fusion-inline-sep\">|<\/span><\/p><p>  Free webinar at 1:00 p.m. Eastern time (US), May 20, 2026 Rosa Krajmalnik-Brown, Ph.D., will discuss her research on gut microbiota in individuals with autism who have gastrointestinal (GI) problems. She will share<\/p><\/div><\/article><article class=\"post fusion-column column col col-lg-4 col-md-4 col-sm-4\"><div class=\"fusion-flexslider fusion-flexslider-loading flexslider flexslider-hover-type-none\"><ul class=\"slides\"><li><a href=\"https:\/\/autism.org\/microbiome_dysbiosis_research\/\" aria-label=\"The autism-associated 16p11.2 microdeletion variant impacts the effects of microbiota disturbances on hippocampal development and behavior throughout the lifespan\" class=\"hover-type-none\"><img decoding=\"async\" width=\"700\" height=\"441\" src=\"https:\/\/autism.org\/wp-content\/uploads\/2019\/07\/AdobeStock_205852097-700x441.jpeg\" class=\"attachment-recent-posts size-recent-posts lazyload\" alt=\"Serious male researcher working with his microscope\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%272560%27%20height%3D%271707%27%20viewBox%3D%270%200%202560%201707%27%3E%3Crect%20width%3D%272560%27%20height%3D%271707%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2019\/07\/AdobeStock_205852097-700x441.jpeg\" data-srcset=\"https:\/\/autism.org\/wp-content\/uploads\/2019\/07\/AdobeStock_205852097-320x202.jpeg 320w, https:\/\/autism.org\/wp-content\/uploads\/2019\/07\/AdobeStock_205852097-700x441.jpeg 700w\" data-sizes=\"auto\" \/><\/a><\/li><\/ul><\/div><div class=\"recent-posts-content\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2025-05-28T22:09:35-05:00<\/span><h4 class=\"entry-title\"><a href=\"https:\/\/autism.org\/microbiome_dysbiosis_research\/\">The autism-associated 16p11.2 microdeletion variant impacts the effects of microbiota disturbances on hippocampal development and behavior throughout the lifespan<\/a><\/h4><p class=\"meta\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2025-05-28T22:09:35-05:00<\/span><span>May 27th, 2025<\/span><span class=\"fusion-inline-sep\">|<\/span><a href=\"https:\/\/autism.org\/category\/biomarkers\/\" rel=\"category tag\">Biomarkers<\/a>, <a href=\"https:\/\/autism.org\/category\/gastrointestinal\/\" rel=\"category tag\">Gastrointestinal<\/a>, <a href=\"https:\/\/autism.org\/category\/health\/\" rel=\"category tag\">Health<\/a>, <a href=\"https:\/\/autism.org\/category\/medical-care\/\" rel=\"category tag\">Medical Care<\/a>, <a href=\"https:\/\/autism.org\/category\/research\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/research-webinar\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/webinars\/\" rel=\"category tag\">Webinar<\/a><span class=\"fusion-inline-sep\">|<\/span><\/p><p>     Handouts are online\u00a0HERE Approximately 17% of children are diagnosed with NDDs, including ASD, ADHD, and ID, which are highly heterogenous, frequently co-occur, and manifest in early life in sex-dependent fashion.<\/p><\/div><\/article><article class=\"post fusion-column column col col-lg-4 col-md-4 col-sm-4\"><div class=\"fusion-flexslider fusion-flexslider-loading flexslider flexslider-hover-type-none\"><ul class=\"slides\"><li><a href=\"https:\/\/autism.org\/autism-and-gastrointestinal-comorbidities\/\" aria-label=\"Autism and Gastrointestinal Comorbidities &#8211; Research Updates\" class=\"hover-type-none\"><img decoding=\"async\" width=\"700\" height=\"441\" src=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/02\/gastro-banner-700x441.png\" class=\"attachment-recent-posts size-recent-posts lazyload\" alt=\"Close-up of a gut scan showing detailed internal structures\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%272560%27%20height%3D%271133%27%20viewBox%3D%270%200%202560%201133%27%3E%3Crect%20width%3D%272560%27%20height%3D%271133%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/02\/gastro-banner-700x441.png\" data-srcset=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/02\/gastro-banner-320x202.png 320w, https:\/\/autism.org\/wp-content\/uploads\/2023\/02\/gastro-banner-700x441.png 700w\" data-sizes=\"auto\" \/><\/a><\/li><\/ul><\/div><div class=\"recent-posts-content\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2025-08-25T11:44:52-05:00<\/span><h4 class=\"entry-title\"><a href=\"https:\/\/autism.org\/autism-and-gastrointestinal-comorbidities\/\">Autism and Gastrointestinal Comorbidities &#8211; Research Updates<\/a><\/h4><p class=\"meta\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2025-08-25T11:44:52-05:00<\/span><span>March 20th, 2025<\/span><span class=\"fusion-inline-sep\">|<\/span><a href=\"https:\/\/autism.org\/category\/anxiety-2\/\" rel=\"category tag\">Anxiety<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/gastrointestinal-webinar\/\" rel=\"category tag\">Gastrointestinal<\/a>, <a href=\"https:\/\/autism.org\/category\/health\/\" rel=\"category tag\">Health<\/a>, <a href=\"https:\/\/autism.org\/category\/medical-care\/\" rel=\"category tag\">Medical Care<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/meltdowns\/\" rel=\"category tag\">Meltdowns<\/a>, <a href=\"https:\/\/autism.org\/category\/news\/\" rel=\"category tag\">News<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/nutrition\/\" rel=\"category tag\">Nutrition<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/research-webinar\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/self-care\/\" rel=\"category tag\">Self Care<\/a>, <a href=\"https:\/\/autism.org\/category\/self-injury-2\/\" rel=\"category tag\">Self Injury<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/self-injury\/\" rel=\"category tag\">Self-Injury<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/sensory\/\" rel=\"category tag\">Sensory<\/a>, <a href=\"https:\/\/autism.org\/webinars\/\" rel=\"category tag\">Webinar<\/a><span class=\"fusion-inline-sep\">|<\/span><\/p><p>   Mojdeh Mostafavi, MD, describes gastrointestinal conditions commonly seen in individuals with autism, including gastroesophageal reflux disease (GERD), inflammatory bowel disease (IBD), Eosinophilic GI disease (EGID), avoidant\/restrictive food intake disorder (ARFID), disorders of<\/p><\/div><\/article><article class=\"post fusion-column column col col-lg-4 col-md-4 col-sm-4\"><div class=\"fusion-flexslider fusion-flexslider-loading flexslider flexslider-hover-type-none\"><ul class=\"slides\"><li><a href=\"https:\/\/autism.org\/food-adverse-reaction-and-intestinal-microbiota\/\" aria-label=\"Food Adverse Reaction and Intestinal Microbiota\" class=\"hover-type-none\"><img decoding=\"async\" width=\"700\" height=\"441\" src=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/08\/gut-microbiome-again-700x441.jpeg\" class=\"attachment-recent-posts size-recent-posts lazyload\" alt=\"Black and white drawing for human torso with multicolored bacteria and yeasts in digestive tract\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%272560%27%20height%3D%271706%27%20viewBox%3D%270%200%202560%201706%27%3E%3Crect%20width%3D%272560%27%20height%3D%271706%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/08\/gut-microbiome-again-700x441.jpeg\" data-srcset=\"https:\/\/autism.org\/wp-content\/uploads\/2023\/08\/gut-microbiome-again-320x202.jpeg 320w, https:\/\/autism.org\/wp-content\/uploads\/2023\/08\/gut-microbiome-again-700x441.jpeg 700w\" data-sizes=\"auto\" \/><\/a><\/li><\/ul><\/div><div class=\"recent-posts-content\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2024-10-14T14:54:54-05:00<\/span><h4 class=\"entry-title\"><a href=\"https:\/\/autism.org\/food-adverse-reaction-and-intestinal-microbiota\/\">Food Adverse Reaction and Intestinal Microbiota<\/a><\/h4><p class=\"meta\"><span class=\"vcard\" style=\"display: none;\"><span class=\"fn\"><a href=\"https:\/\/autism.org\/author\/melanie\/\" title=\"Posts by Melanie Glock\" rel=\"author\">Melanie Glock<\/a><\/span><\/span><span class=\"updated\" style=\"display:none;\">2024-10-14T14:54:54-05:00<\/span><span>September 10th, 2024<\/span><span class=\"fusion-inline-sep\">|<\/span><a href=\"https:\/\/autism.org\/category\/gastrointestinal\/\" rel=\"category tag\">Gastrointestinal<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/gastrointestinal-webinar\/\" rel=\"category tag\">Gastrointestinal<\/a>, <a href=\"https:\/\/autism.org\/category\/news\/\" rel=\"category tag\">News<\/a>, <a href=\"https:\/\/autism.org\/category\/webinar\/nutrition\/\" rel=\"category tag\">Nutrition<\/a>, <a href=\"https:\/\/autism.org\/category\/research\/\" rel=\"category tag\">Research<\/a>, <a href=\"https:\/\/autism.org\/category\/wao\/\" rel=\"category tag\">WAO<\/a>, <a href=\"https:\/\/autism.org\/webinars\/\" rel=\"category tag\">Webinar<\/a><span class=\"fusion-inline-sep\">|<\/span><\/p><p>     This is a joint presentation by ARI and the World Autism Organisation.  Professor Carmelo Rizzo, MD, discusses adverse reactions to food and the critical role of intestinal microbiota in<\/p><\/div><\/article><\/section><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":8410,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9449,21,80,85,31,3782,9475,24],"tags":[4895,3920,6200,5448],"class_list":["post-16995","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-anxiety-2","category-autism-spectrum-disorders","category-gastrointestinal","category-gastrointestinal-webinar","category-immune-issues","category-neurological","category-ways-to-help","category-webinar","tag-gastrointestinal-issues","tag-gi-issues","tag-microbiome-research-in-asd-parker","tag-research-on-microbiota-transfer-therapy-in-patients-with-asd","webinar-author-calliope-holingue-mph-phd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.6 (Yoast SEO v27.1.1) - 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